Welcome! Like everyone else, I've never heard of this setup you're suggesting - given that a handful of experienced and respected folks around here have weighed in with the same conclusion, I'd be extremely cautious (read: I wouldn't buy it).
I'm not an iStick fan, only because I seem to be one of the many who received a defective unit with loose electrical connections, bad threads, and other shortcomings. Some people like it, though.
@UncleRJ loves him some Sig 30 - I love my Sig 100 and would probably love me some Sig 30 if it delivered enough power for my toppers...if you're going to go sub-ohm on anything other than a Kanger Subtank, I'd keep looking, but for a last-gen clearo like an AeroTank or Nautilus (or the Subtank) it sounds like an absolute winner. I've heard good things about the Smowell 50 and 65 devices, may have to pick one up just to see what the hype is about, since the popular mid-level mods that initially appealed to me (iStick 50, Smok M80) have been getting lots of bad press lately.