Hi and welcome to VU.
First of all, the claptons, fused clapton, alien, etc etc etc coils all have 1 thing in common. Spaces in the coil to trap more ejuice which produces a better flavor. These are all flavor builds.
For clouds, you have basically 4 builds. Straight single coil (x2) So 6 wraps of 20ga kanthal dual coil.
Next you have a dual parrallel coil... 2 strands of 24 ga kanthal, 5 wraps, and dual coil.
Then you have a quad coil.. 5 wraps 24 ga kanthal x4 coils
and a kissing quad coil. 5 wraps 24ga kanthal x4 but the coils on each side share 1 post in the middle and they touch at the 2 middle ends.
Mainly it depends on how much deck space you have to work with. Rule of thumb is that the more surface area your coil has, the move cloud is produced. Cloud coils are built to be painted every time before each pull, at high wattage and high airflow. The atomizer makes a difference too. A tsunami is a flavor RDA while a mutationX V4 is a cloud RDA (18 air holes, 9 per side plus 2 pipes in the base)
When building a cloud coil, you also have to consider the limit of your mod. A 100w mod will not fire as large a coil as a 200w mod will.
Now twisted wire has only 1 advantage. It doesn't seperate while you are wrapping it. You get more surface area from a dual parallel coil, and better flavor from a 2 core fused clapton.
Other factors in cloud chasing include lung capacity, inhale and exhale technique and mouth position.