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Jimi's Daily Health Articles

Rhianne

Diamond Contributor
Member For 2 Years
ECF Refugee
The 30-Second Toxin Flush: The Easiest Way to Naturally Detox
https://yurielkaim.com/toxin-flush/

Hidey hi, Jimi. This was a good article. I just got some green powder from Body Ecology; it’s fermented. I also have Braggs ACV, but I’ll need lemons. Can I use a good organic lemon juice to detox? I had some but I used it up in ice tea I make with organic tea.
Been feeling yuchy for the last few days. My tummy is getting over something (diarrhea) and I’m having a cough when I vape a lot of my juice. I’ve got to get more Palm Max VG stuff. I keep trying to cheat with 70/30 juice I have, but it’s making me have a dry cough.

Hope you’re doing great. And that the garden is growing well. Miss all of you, but my dh wants me to chill out this week.
Big hugs to you, my friend. :cheers:


Sent from my iPad using Tapatalk
 

Jimi

Diamond Contributor
Member For 5 Years
Hi Rhianne, Thank you, glad you liked it. Well I imagine it would work in a bind, unless for some reason the oxidation of being processed would interfere, plus you never know what stage of ripeness they were picked, yes it does make a difference:D. But to me there's nothing like the real thing;). Lemons are a staple here, we go through a load of them;).
 

Jimi

Diamond Contributor
Member For 5 Years
Hidey hi, Jimi. This was a good article. I just got some green powder from Body Ecology; it’s fermented. I also have Braggs ACV, but I’ll need lemons. Can I use a good organic lemon juice to detox? I had some but I used it up in ice tea I make with organic tea.
Been feeling yuchy for the last few days. My tummy is getting over something (diarrhea) and I’m having a cough when I vape a lot of my juice. I’ve got to get more Palm Max VG stuff. I keep trying to cheat with 70/30 juice I have, but it’s making me have a dry cough.

Hope you’re doing great. And that the garden is growing well. Miss all of you, but my dh wants me to chill out this week.
Big hugs to you, my friend. :cheers:


Sent from my iPad using Tapatalk
Hi @Rhianne
O.k. for your breathing, I posted an article on breathing exercises "THAT EVERY VAPER SHOULD DO EVERY MORNING WHEN THEY GET UP AND EVERY NIGHT BEFORE BED" but I will give you the brief of it.
Oxygen is one of the most healing promoting elements on the planet, it has a healing effect on all diseases so the more you can take in the better. Many people are guilty of sub-consciencely shallow breathing and "NOT" making a complete exhale, this leads to a whole array of diseases:eek:. It's human:rolleyes:. So to rectify the situation we all should do breathing exercises. I have been doing these for a couple months and they have improved my overall health aside making my breathing so very much better.
O.k. here we go:
Sit on the side of your bed, upright w/good posture, arms relaxed on your legs. Now take a regular breath hold 2 seconds and exhale with force, while exhaling cross your arms and press them into the area just below the ribs, this w/forced exhale will force every bit of air out of your lungs that you can exhale .
then take as deep of breath as you possibly can through your nose to refill your lungs, hold 2 seconds and do the exhale step again. Do at least 15 repetitions, I do sets of 25 morning and night and can breath so much better;).
To help ward off the sickness this season try some cordial silver spray;) Teachers use it to keep from being sick all the time, TRY IT YOU'LL BE SURPRISED OF THE DIFFERENCE IN A COUPLE WEEKS:cool::cool:
 
Last edited:

Jimi

Diamond Contributor
Member For 5 Years
1 article, two posts......Part 1
Fruit Juices Not as Healthy
as Most People Assume

In a world where people drink soda by the gallon (I used to know a woman who had a Coke for breakfast), fruit juice would seem to be the height of good sense. Just about the perfect health habit.

And fruit juices do contain tons of vitamins, minerals and other nutrients it would take a very large book to describe. Sad to say, they also contain a megadose of sugar in a form – liquid – that the body absorbs fast.

Excess dietary sugar is linked to overweight and obesity, type 2 diabetes, high blood pressure and cardiovascular disease.

As for cancer, there haven't been enough human studies to prove a direct link to sugar, but the indirect links are overwhelming. Overweight people and those with diabetes or merely prediabetes are at much higher risk of cancer.

And the sheer physiology of cancer suggests sugar must increase your risk: cancer cells take up sugar at a far higher rate than healthy cells. To them it’s a superfood.

So a research group from France decided to carry out a study focusing on sugar sweetened drinks including natural fruit juices.

For lovers of freshly squeezed orange juice, the findings are a bit disturbing. .
.
Strong link to heart disease and diabetes

In the 26 years between 1990 and 2016, the consumption of sugary drinks rose by 40%.

Researchers have thoroughly studied the impact this huge increase has had on cardiovascular disease.

A major study published in the Journal of the American Medical Association in 2017 found that "SSBs [sugar sweetened beverages] were the leading estimated factor associated with cardiometabolic mortality between ages 25 and 64 years..."

Cardiometabolic refers to fatty deposits in the arteries together with blood sugar irregularities. The number of deaths in the US attributable to these factors from sugary drinks was estimated to be 24,000 in the year 2010.

24,000 additional deaths in just one year from sugary drinks.

Switching to artificially sweetened drinks was initially considered to be an ideal way to lower the risk, but, as Cancer Defeated readers know, these sweeteners themselves turned out to be deadly. They’re linked to a higher incidence of hypertension, type 2 diabetes, obesity, and blood sugar fluctuations.

Trying to measure cancer risk

Since the potential link between sugary drinks and cancer has been little studied compared to cardiovascular disease, researchers from the Sorbonne study center in Paris and the French public health agency took a crack at it. They tracked 101,257 adults, of whom 79% were women, taking part in the NutriNet-Santé study.

This is an ongoing web-based investigation into the impact of diet and lifestyle on health outcomes and mortality in the French population. Everyone taking part is aged 18 and over. Their average age is 42.

Participants' food consumption was assessed from repeated food intake questionnaires for 3,300 different foods and drinks over a period of up to nine years. It included 97 sugary drinks, defined as having more than 5% sugar, and 12 artificially sweetened beverages.

To ensure their findings were as robust as possible, the volunteers had to fill in five questionnaires in total which asked a number of questions about their background and lifestyle.

These included age, gender, height, weight (which was collected every six months), educational level, smoking status, physical activity, family history of disease, menopausal status, and drug use.

The statisticians took into account all these factors and others that could influence the onset of cancer. The research was published in the British Medical Journal in July.

Fruit juice ups cancer risk by 12%

Over the course of the study, 2,193 people were diagnosed with cancer for the first time. Among them were 693 with breast cancer, 291 cases of prostate cancer and another 166 with colorectal cancer.

First, let’s look at the way ALL sugary drinks contributed to these cancer cases.

The results showed that cancer risk grew in proportion to the volume of sugary drinks, including fruit drinks, a participant consumed. Compared to those in the bottom quarter of sugary drink consumption, those in the highest quarter had a 30% greater risk for any form of cancer and a 37% greater risk of breast cancer.

The study doesn’t say what volume of sugary drinks was downed by these folks, but remember they were in the one-fourth of the whole group that drank the most. If I'm interpreting the tables correctly the amount of total sugary drinks consumed in each quartile was an average of 27.6 ml per day, 57.0, 101.4 and – in the high sugar consumers who had the most cancer -- 185.5.

Every 100 ml (nearly 3.5 ounces) increase was linked to an 18% raised risk for cancer overall and a 22% increased risk for breast cancer, compared to the baseline. These are high, scary increases from not even a half cup of the drink.

No link was found for either prostate or colorectal cancer, but this may be because there weren't enough people with these forms of the disease to establish a link. Remember that four out of five of the participants in the study were women so this study doesn’t tell us much about prostate cancer.

Artificial sweeteners were given a clean bill of health. Same goes for water and unsweetened tea and coffee.

Risks of fruit juice identified

But. . . the news was disappointing for those drinking 'healthy' fruit juice purchased from a health food store or who make their own freshly squeezed variety.

The researchers found consumption of pure, 100% fruit juice was significantly associated with the risk of overall cancer. The increased risk was 12% for every 100 ml per day consumed.

That’s not as bad as the 18% increase for sugary drinks in general, but it’s too high for me. I can’t rate fruit juice as a healthy choice.

What might be even more important is that the study marked the first substantial piece of research to link sugar with cancer.

Lead researcher Mathilde Touvier said, "We cannot make a causal inference, but we took into account many demographic and lifestyle factors and the association was still significant.

"The idea is not to avoid foods, just balance the intake. If you consume from time to time a sugary drink it won't be a problem, but if you drink at least one glass a day it can raise the risk of several diseases -- here maybe cancer."

Nikolai Petrovsky, Professor of Medicine at Flinders University in Australia, and Director of the Department of Diabetes and Endocrinology at Flinders Medical Center, had this to say regarding so called healthy juices:

"The population continues to be conned into thinking that 'natural' automatically equates to 'healthier' which is simply not the case.

"High sugar natural fruit drinks, which are flourishing worldwide and being marketed as a healthier option by juice and smoothie companies, can be just as bad, if not worse, than the carbonated drinks they are attempting to replace, as in many cases they can have an even higher total sugar content."

One of the authors mentioned that other factors may make a
difference --
 

Jimi

Diamond Contributor
Member For 5 Years
Part 2

Possible mechanisms

Since obesity is strongly linked to cancer, and sugar is strongly tied to obesity, is this where the connection lies?

Dr. Touvier said that weight gain and obesity caused by excess consumption of sugary drinks "played a role in the association, but they did not explain the whole association."

So what does explain it? The researchers admit they don't know, the study wasn't designed to assess this, but they did suggest possible drivers other than weight gain.

Visceral adiposity: Fat stored around the abdomen, adjacent to many organs such as the liver, pancreas and intestines, influences hormonal function. Sugary drinks are a cause of these visceral fat deposits.

An excess of this biologically active tissue (often seen as pear-shaped, middle-age spread) is connected to many health problems. Emerging evidence links it to cancer, by way of alterations in cell signaling proteins secreted by adipose tissue and in cell signaling pathways.

I’ll just mention that this tissue is also rich in stem cells, so it does seem fat tissue isn’t something that just sits inertly in your body.

What’s more, this tissue harbors an abundance of inflammatory cells that create systemic inflammation and a cancer-friendly environment.

Population studies have already linked excess visceral adiposity to cancers of the breast, colon/rectum and esophagus.

High glycemic index/load: Rapidly absorbed, high-glycemic-index carbohydrates from sugary drinks lead to an abundance of circulating insulin, insulin resistance, and type 2 diabetes.

Their high glycemic load increases pro-inflammatory markers such as C reactive protein and causes systemic inflammation.

All these factors have been related to breast cancer, liver cancer and cancers linked to diabetes.

Whole fruit contains fiber that slows down absorption and makes it less likely you’ll experience spikes in blood sugar and insulin. I can’t say that whole fruit eliminates the risks seen in juice, but it probably reduces them.

Advanced glycation end products (AGEs): A high dietary sugar intake can lead to the creation of harmful chemicals when sugar bonds with proteins. When AGEs accumulate in tissues they increase inflammation in the body and increase cancer risk.

Time to ditch the morning orange juice?

Dr. Touvier suggests we should only drink fruit juice from time to time and certainly not as much as a cup, which is 236 ml or half a pint.

Switch to oranges, if you must eat fruit. They’re more filling. While a cup of orange juice contains nearly all the sugar from two or three oranges (depending on the size of the oranges), eating one whole orange will probably fill you up.

The peel and flesh of an orange are far more beneficial, in nutritional terms, than the juice, and they also contain compounds with potent anti-cancer activity. I don’t imagine there will be a rush to eat the peel, but it’s good for you.

Allison Hodge, an associate professor at Australia's University of Melbourne and senior research fellow at Cancer Council Victoria, analyzed the French research and offered a take home message.

"This is more reason to reduce consumption of sugary drinks and replace them with water, and consume whole fruits to obtain the vitamins they provide."
 

Jimi

Diamond Contributor
Member For 5 Years
I seen this today and it's so true , I wanted to share it with all:):)

What Does A REAL Friendship Look Like?

During various decades of my life, I've had a few “Best Friends”.

They first started in elementary school, junior high, high school and then college.

And then as I grew older and entered my 20s, 30s, 40s, 50s, and now 60s, some of my friends traveled the distance with me.

We went through dating experiences, marriages, divorces, careers and motherhood together. There were many ups and downs, through our lives. But the one common thread was that those “Best Friends’ stayed with me through all my successes AND failures.

As I look at those past and present friendships I had with men and women, I found the true definition of friendship for me. Maybe it will resonate with you, too.

This is my definition of a TRUE friend...

Anyone who has a Soulful Bond is a friend who would do anything for you, who revels in your happiness and is there to comfort you in your sadness and gets it exactly.

It's the people who feel the same pride and joy for me as I do for them.

There's no spirit of competition or desire to be, and do “better than each other”.

We celebrate one another! You take turns celebrating each other's wins and lift one another up to comfort and love one another when we experience difficulties and heartaches. We're on equal terms. One person is not above another.

We don't perceive that either one of us is in the shadow or the light of one another. If that happens, with your bestie, you can sense it and it keeps each of you from being open and truly trusting one another.

A true friend can't be jealous of you or want to take advantage of you in anyway!

It's important to treat your “Bestie” or Besties with respect and regard.

I know these kinds of friendships are hard to find. It requires discernment.

I have a couple of Besties in my life. There are actually five women and two men that I know love me and are my biggest cheerleaders in my life, as I am in theirs’. It's reciprocal and it must be to be equal.

I can tell them anything! And sometimes when I share my true feelings about certain situations, it's not always pretty or uplifting. But they listen anyway and will share their opinions, suggestions, tell me stories of their own struggles and share how they overcame them.

And I can freely share my wins without feeling like I'm bragging, or selfish or thinking that I'm better than them!

They celebrate with me, and without feeling jealous, or less than.

You know and can feel when you're truly loved unconditionally and supported.

I have a particular bestie girlfriend who ALWAYS tells me the truth. Even if it's difficult for me to hear. However, I never question her motive because she ALWAYS wants the best for me. She's also my biggest supporter! She reads everything I write, listens to all my Summits and almost every morning sends me a text or email to let me know how much she appreciated and learned from my writings.

And because of her love and support for me, I trust her. And I know if anyone would say anything negative about me, she would have my back.

I know and understand quite well how girls and women can be very competitive with one another, even with their closest girlfriends. It can be very hurtful.

We're not here to tear each other down so that we can lift ourselves up and be “Better” than one another. That's very destructive.

We're here to love and support each other.

If the green eyed monster rises up in you, look within yourself and ask “why am I feeling this way towards my girlfriend”? It's usually a sign of low self-esteem. You aren't happy with where your life is going.

Don't blame a sister; look within and find the answer. Write about it instead of gossiping or talking badly about her just because you're triggered and jealous.

True friendship includes listening, talking, listening some more, laughing, crying, building dreams together, truthfulness, cheering each other on, supporting and speaking your truth.

Don't allow jealousy to end some amazing, loving wonderful friendships. You'll know and recognize who truly is your friend and who isn't.

Ask for discernment, and watch their actions towards you, not just their words. If it doesn't feel good being around them, then keep them out of your life and make space for the REAL friends.

So in closing, I want to share some tips on how to have lasting friendships.




    • Remember the Golden Rule - Treat others the way you want to be treated. Don't treat them above or below you, treat them like an equal.
    • Realize that NO ONE is perfect! We all have quirks and flaws; and accepting each other's flaws is key. Don't judge your friend.
    • Respect one another's opinions. Your friends are allowed to have a different opinion than you, that's what makes us all individuals.
    • Realize that even the best of friends can't be together 24/7 and they can have other friends, too! Plus, you don't have to like their other friends!
    • Communicate, communicate, communicate! Friends can't read our minds! If something is affecting your friendship, talk about it! Be honest and truthful!
    • Be a good listener when she needs to talk. And don't make her story about you! Use heart-centered listening.
    • Be trustworthy. Don't share any personal secrets she entrusted you with. Keep and guard her secrets, they're not for you to share without her permission.
    • Keep your word. If you say you're going to do something, then do it! Actions speak louder than words.
    • Don't talk or gossip behind your friends back. Gossip is toxic and the biggest killer of trust.
    • Don't expect your friendships to be perfect. We're all messy people! Allow each other space, and don't take actions personally. If you're wondering about something, ask her! Give her the benefit of the doubt, as you would want the same.
Remember to laugh, listen and be kind.

I love Mother Teresa's quote “Let no one ever come to you without leaving them feeling better and happier”!


 

Jimi

Diamond Contributor
Member For 5 Years
Thought for today:

Illnesses do not come upon us out of the blue. They are developed from small daily sins against Nature. When enough sins have accumulated, illnesses will suddenly appear.

Hippocrates father of medicine
 

Rhianne

Diamond Contributor
Member For 2 Years
ECF Refugee
Hi @Rhianne
O.k. for your breathing, I posted an article on breathing exercises "THAT EVERY VAPER SHOULD DO EVERY MORNING WHEN THEY GET UP AND EVERY NIGHT BEFORE BED" but I will give you the brief of it.
Oxygen is one of the most healing promoting elements on the planet, it has a healing effect on all diseases so the more you can take in the better. Many people are guilty of sub-consciencely shallow breathing and "NOT" making a complete exhale, this leads to a whole array of diseases:eek:. It's human:rolleyes:. So to rectify the situation we all should do breathing exercises. I have been doing these for a couple months and they have improved my overall health aside making my breathing so very much better.
O.k. here we go:
Sit on the side of your bed, upright w/good posture, arms relaxed on your legs. Now take a regular breath hold 2 seconds and exhale with force, while exhaling cross your arms and press them into the area just below the ribs, this w/forced exhale will force every bit of air out of your lungs that you can exhale .
then take as deep of breath as you possibly can through your nose to refill your lungs, hold 2 seconds and do the exhale step again. Do at least 15 repetitions, I do sets of 25 morning and night and can breath so much better;).
To help ward off the sickness this season try some cordial silver spray;) Teachers use it to keep from being sick all the time, TRY IT YOU'LL BE SURPRISED OF THE DIFFERENCE IN A COUPLE WEEKS:cool::cool:

Thank you, Jimi. How’s it going, my friend? Hope the garden got enough rain! Thanks for the breathing exercises.
My dh likes to make colloidal silver at home. I just bought some echinacea with elderberry caps since it usually helps with any infections I may get. I’ll have my hubs make some more silver, too. He likes being a mad alchemist.
I’ll see you on the music game in a few days. :hug: :wave: :hug:


Sent from my iPad using Tapatalk
 

Jimi

Diamond Contributor
Member For 5 Years
You're very welcome Rhianne, It's going good here, thank you for asking my friend. my garden is doing fantastic this run,everything came up better than in the spring and every year that I have made a late run of beans I never get bean beetles:bliss:, I am just hoping the frost holds off here for 60 more days;). I make my own cordial silver too;) and always have a bottle or two on hand, it's very good immune support and they get a fortune for it in the vitamin stores:eek:.
o.k. catch you later:wave:
 

Rhianne

Diamond Contributor
Member For 2 Years
ECF Refugee
You're very welcome Rhianne, It's going good here, thank you for asking my friend. my garden is doing fantastic this run,everything came up better than in the spring and every year that I have made a late run of beans I never get bean beetles:bliss:, I am just hoping the frost holds off here for 60 more days;). I make my own cordial silver too;) and always have a bottle or two on hand, it's very good immune support and they get a fortune for it in the vitamin stores:eek:.
o.k. catch you later:wave:

Jimi, thanks for the articles and the advice. Glad to hear your beans are doing well. And I’m sure you are too, my friend.
:big hugs: :wave: :blowkiss:



Sent from my iPad using Tapatalk
 

Jimi

Diamond Contributor
Member For 5 Years
NAC is Proven Effective Against Brain Problems

I was a late convert to the wonders of NAC (N-acetyl cysteine), a well-known nutrient. Somehow I overlooked it.

But now I’m a full believer and proselytizer. I got religion when I learned that NAC is perhaps the most effective way to boost your glutathione levels, one of the most important markers for how long you’re likely to live.

NAC pretty much benefits every part of your body, including your brain. Now it turns out it has specific power to help out with Parkinson’s disease and other brain pathologies. If you’re not taking NAC already, you’ll want to after you read this. . .

Your brain enters troubled waters when the neurons that produce the neurotransmitter dopamine start to die.

These neurons help you control your muscles. They keep you on the go because they’re part of the reward system in the brain. They offer up the satisfaction you feel when you work hard and obtain what you worked for. Or when you eat a delicious meal.

Besides that, you need those neurons to keep your memory working properly.

If you lose a good number of them – which happens in people with Parkinson’s disease – you suffer a long list of physical and mental issues. Simple movements become difficult or impossible. You start losing the ability to remember things.

So far, all the mainstream medical treatments for Parkinson’s aimed at keeping dopamine supplied to your brain are only temporary fixes. They produce only short-term improvements.

That’s what prompted researchers to look at a natural substance, NAC, to see if it might help. The results of their tests are promising, which is a great thing for people like us who are concerned with our brain health.

Conserve Your Antioxidants

NAC is an antioxidant. In fact, it’s one of the most powerful antioxidants known. It’s been used to treat certain types of drug poisoning.

The nutrient provides some of the raw material the body needs to make its own glutathione, which is manufactured in all cells. (The liver also makes extra amounts of glutathione that are distributed throughout the body.)

And as researchers have taken a deep dive into how NAC can be used to treat the brain disruption that takes place during Parkinson’s disease, their results are leading them to advocate making it a standard treatment for this disease.

One group of these researchers, working at Thomas Jefferson University in Philadelphia, analyzed what happens when people with Parkinson’s get extra amounts of NAC.

They found that damage to the dopamine-producing neurons in the brain seems to result from a steady build-up of oxidative stress caused by free radicals. The brain’s levels of glutathione tumble.

Considering that previous tests have shown supplementing with NAC can increase glutathione in the brain, the Thomas Jefferson scientists used both NAC supplements taken orally and NAC administered intravenously to track its effects.

For three months, along with conventional treatment, the Parkinson’s patients in the study were given intravenous infusions once a week and, on the days they didn’t get the intravenous infusions, they took 500 mg of NAC by mouth twice a day.

The study shows that compared to Parkinson’s patients who only received conventional care, their disabilities linked to Parkinson’s backed off by about 14 percent and their dopamine function improved by four to nine percent.1

"This is an exciting study that suggests a natural molecule such as NAC can help improve dopamine function and symptoms in Parkinson's patients," says Dr. Andrew Newberg, who directs research at the Department of Integrative Medicine and Nutritional Sciences at Jefferson.

NAC for the Whole Body

As I mentioned, NAC showers you with many benefits besides protection from Parkinson’s. Here are just a few more. . .

  • Useful for treating concussions: A study at the University of Maryland shows that NAC can help keep the blood/brain barrier working better after a concussion. When this barrier is impaired, toxins from the bloodstream can enter the brain. (The same sort of blood/brain barrier malfunction can take place after military personnel are exposed to explosions.)2
  • Produces benefits for skin problems: A review study at Loyola University explains that NAC can help clear up acne and protect the skin from sun damage. Although the researchers stress that NAC is not useful as a sunscreen, applying it to the skin increases the skin’s resistance to oxidative damage caused by the sun’s ultraviolet rays.3
  • Improves your heart health: Taking NAC has been shown to lower the level of homocysteine in the body (a risk factor for heart disease).4 In a study where it was taken with the amino acid l-arginine, it lowered blood pressure.5
You can see why I agree with experts who say everyone middle-aged and older should take NAC to support the level of glutathione in the body – which drops as the years go by. I suggest you check out Vital Force, the glutathione–boosting supplement from our sister company Green Valley Natural Solutions. It not only includes a clinical dose of NAC, but it contains other nutrients designed to raise your glutathione level.

You can buy NAC by itself from numerous vendors, but Vital Force also gives you proprietary ingredients that boost your glutathione even more. Plus the quality is guaranteed. The longer I’ve been involved with the supplement business, the more I’ve learned that quality is compromised all over the place and there’s also a great deal of outright sleaze.
 

Jimi

Diamond Contributor
Member For 5 Years
One article 2 posts
Caught Red-Handed Scamming
and Faking “Science”

"Ho ho ho. Come quietly, it’s a fair cop!” (Translation from the English: Ha ha! We’ve caught you red-handed in a criminal act. Best come along quietly to the police station. Don’t make a fuss”!)

Usually it takes years, or even decades, before the lies and abuses of Big Pharma show up. Meanwhile, the drug company has made a killing in sales and doesn’t care. Sometimes there’s even a fine of a few million dollars, even a few hundred million, as with Merck and Vioxx. But when sales are in the $billions, why should they care?

This time though, the fraudsters must have been shocked to be discovered in the very act, by an international consortium. They probably thought they had years to exploit the scam. So what’s going on?

A group of scientists from leading institutions is questioning the findings of a prominent immunology article linked to a strategic drug development partnership potentially worth up to $183 million (164 million euros). Follow the money, eh?

The original article, published in the journal Cell in 2016, describes studies of the immune systems of patients with rare autoimmune (APS-1). The disease results from mutations in the autoimmune regulator (AIRE) gene that in healthy people plays a role in training immune cells not to attack the body's own tissue.

Even if you don't quite understand the gobbledegook, understand this: it could open a doorway to widespread treatment of autoimmune diseases and, since autoimmune diseases are now so common, this means LOTSA MONEY for Big Pharma.

Never wanting to earn an honest $billion, when a crooked $10 million is out there, Big Pharma, of course, plumps for crime, every time!


This is how it unfolds…
In an article published in the journal eLife last month, scientists from institutions that include the Karolinska Institute in Sweden, the University of California SF, Stanford University, and the National Institute of Allergy and Infectious Diseases report that they attempted to replicate some of the results from the 2016 Cellarticle and were unable to do so.

Now I have said many times in my reports that the Karolinska Institute in Sweden is above reproach. I don't mean they never make mistakes. But they don't LIE prodigiously like American centers of science. So I trust the Karolinska.

mail

The Karolinska Institute. Stockholm, Sweden.
Therefore, when they, and the other three study centers, say they "can't replicate" the published findings, it almost certainly means something bogus is going in. YES, MEDICAL JOURNALS DO PUBLISH COMPLETELY FALSE PAPERS (OFTEN), SOMETIMES EVEN WITH INVENTED "RESEARCHERS"!

Big Pharma's dirty fingers are in there, always, to the point where published science has almost meaningless credibility; you can choose to believe it or not believe is, as you like. But if you openly criticize a study, they will probably arrange for you to quietly "disappear" [No, not the concrete shoes! But your article will be quietly withdrawn]

Now they have a problem; 3 world-class research centers say "It looks like you're lying"! (only they put it politely and say "We can't replicate your findings.") That's going to be hard to bury.

They challenge two of the original article's findings: that patients with APS-1 produced a much wider range of antibodies against their own bodies' tissues than previously described. Secondly, that the antibodies "discovered" seemed to protect against diabetes. Again, this is a HUGE market. Diabetes and pre-diabetes are on the rise to the point where over 50% of the US population has one or the other. And as I reported recently, an incredible 88% of Americans did not have full healthy markers for glucose metabolism.

Anyway, these possibly-illusory antibodies became the focus of a development partnership between the France-headquartered pharmaceutical company Servier and German biotechnology company ImmunoQure, said ImmunoQure cofounder Adrian Hayday, PhD, a professor and researcher at King's College London and corresponding author of the Cell article.

Servier agreed to pay ImmunoQure up to €164 million ($183 million), which includes an upfront payment of an undisclosed amount and additional payments at milestones in the development process, plus royalties on net sales if the antibody makes it to market. Sounds like a bribe to me! Who wouldn't be careless with the results, when there is nearly $200 million on the table, plus pickings.

Despite the new challenge, a Servier spokesperson said the company's internal data confirm the importance of the supposed antibody pathway in autoimmune diseases, as well as the specificity and neutralizing activity of the antibody cloned by ImmunoQure. Well, they would say that, of course.

 

Jimi

Diamond Contributor
Member For 5 Years
Part 2

Challenging a "Landmark" Article
On the point about the number of antibodies against their own body's molecules that APS-1 patients are supposed to have developed, the challenging scientists make the case that the statistical analysis in the Cell article was skewed to identify significantly more antibodies in the serum of case patients than of control patients.

"We could show that using random data [meaningless figures], we got basically the same result they did," said lead author Nils Landegren, MD, PhD, of the Karolinska Institute in Stockholm, Sweden. "We have a very strong case their results are false." (my addition in brackets).

Landegren and colleagues also ran experiments to test whether the prevention of diabetes theory held water. It did not.


mail

"We did our best using an established method, using positive and negative controls showing the expected result," Landegren said, but they could not see any difference between patients who had type 1 diabetes and those who did not. It will be important for other research groups to try to replicate the experiment in future studies and to see how they fare, Landegren said.

That's good science.

Hayday said his group used the statistical analysis method they did because he was more concerned about ruling out false negative results than false positives when looking for antibodies expressed as "private reactivities" in a few patients, not the cohort as a collective group. That's BAD science…

Translation: bend the result in favor of the findings we want, rather than allowing "false" negatives to screw it up. But to me, that's as good as a confession of malfeasance. Since he's not supposed to know before he starts what the results will be, why would he be skewing the results away from a negative finding?

Hayday sees the difference in statistics as a difference in approach: "When you undertake a statistical treatment of data, there is no silver bullet, you have to use what makes sense."

In the end, it got dirty. Hayday accused the other teams of "shoddy" work! Sounds like someone caught red-handed, doesn't it? When four other study centers, who have no academic or financial bias factors, say his results aren't valid, who would you side with?

Now others have stepped in. London-based pharmaceutical company AstraZeneca and the small French biotech Neovacs, both studies failed their primary endpoints. These recent clinical data are "mixed at best", they said.

Access to ImmunoQure's website currently requires login credentials, but Hayday said that that is unrelated to the recent publication. Oh yeah! The website is being redesigned and will be back up again in about 10 days, he said.

Is this starting to stink a little bit, to you?

One of the scientists who reviewed Hayday's work from 2016 rejected the Karolinska team's criticism and spoke of a "landmark" paper. Another scientist reviewer disagreed: "This appears to warrant a revision to the original conclusions in Cell…"

As for the contested statistical analysis, one reviewer wrote that Landegren's and colleagues' concern is "100% warranted."

Incidentally, the authors of the new critique originally submitted their manuscript to Cell, but it was rejected without an explanation, Landegren said.

And that's just about where the "science" ends, folks. Quibbling, disagreement, almost certain malfeasance, if not fraud, and name calling.

I'm glad I'm out of it. I treated autoimmune diseases with far higher positive outcomes for decades, talking with Mother Nature, prescribing better diet, chemical unburdening, parasites, dysbiosis and sometimes a little psychological "lift"!

Food allergies and environmental chemical sensitivity were by far the most common mediators of autoimmune disease.

I thought I'd just give you a heads up on how they do "science" these days,

 

Jimi

Diamond Contributor
Member For 5 Years
Beware of This Sneaky Carcinogen
in Your Food

Every once in a while, the media stirs up concern about arsenic in our food and drinking water. But after a brief spate of headlines, the concern vanishes.

But the problem doesn’t vanish, and you should do something about it. And some experts believe – with reason – that it might be getting worse.

A number of states are now taking steps to fight back against our arsenic consumption – mostly with filtration systems that limit its level in drinking water. That will help, but it’s not enough. And if you don’t happen to live in one of those places, it’s no help at all.

Too much arsenic in our food and water could pose a long-term, serious cancer risk. Arsenic can significantly lift your risk for lung, bladder and kidney cancer. You probably won’t develop the disease until years from now – and in some cases the cancer occurs decades after exposure.

How did this poison become so widespread, and what can we do to protect ourselves? Keep reading. . .

Only since 1997 has the World Health Organization recognized arsenic in drinking water was a world-wide health issue. Since then, studies show cancer is not the only risk. Consuming food and water contaminated with arsenic increases your risk for heart disease, diabetes and lung problems.

Some exposure to arsenic in your meals and the environment is unavoidable, because the mineral is found naturally at low levels in soil everywhere. Plus, I don’t believe in scaremongering about relatively small boosts in cancer risk that are hard to avoid.

What makes sense are prudent steps any of us can take. Probably the easiest one is to make sure you drink healthy water – not just because of arsenic but a whole raft of other pollutants as well.

It’s useful to know there are two forms of arsenic – organic and inorganic. In this context the word “organic” has nothing to do with organic food and that sort of thing. It’s just a chemical term for molecules containing long chains of carbon atoms.

Inorganic arsenic, which usually occurs as a pollutant from industry, is much more toxic to the body. Organic arsenic is not totally harmless either, but it’s not as much of a risk.

Contaminated food and water

A big problem today, however, is that inorganic arsenic is showing up in ever-larger amounts in many foods, and can be especially common in water and rice. As a matter of fact, in the summer of 2019 several brands of bottled water had to be recalled from stores like Walmart, Target and Whole Foods because they were too high in arsenic.

Afterwards, the bottled water producer said it was installing filters at its plants designed to take out the arsenic.1 As far as I can gather, the questionable products were store brands, not nationally branded water like Deer Park, Polar Springs or Perrier.

That’s why I’ve always bought nationally branded bottled waters. They have a lot more at stake than a store brand, and a lot more incentive to get things right.

The origin of much of the inorganic arsenic in soil that ends up in food and water stems from chemicals farmers used in the 1950s, 60s and 70s. After that, the pesticides and herbicides containing arsenic were taken off the market.

This did not solve the problem of the estimated 1.6 million tons of arsenic-laden chemicals that had been dumped on farmland before the ban. Some of it lingers on and is still being absorbed by food crops.

Arsenic in rice

Rice has proven to be one of the most troubling foods in terms of arsenic contamination. Exactly how troubled we should be is a matter of debate.

But following tests at Dartmouth, the researchers were forced to conclude, “Our findings suggest that many people in the United States may be exposed to potentially harmful levels of arsenic through rice consumption.”2 As analyses have shown, rice generally contains ten times as much arsenic as other grains.3

The Dartmouth study found that the level of arsenic in your blood generally rises in proportion to the amount of rice you eat.

The relatively high levels of arsenic in rice occur because the plant efficiently absorbs the mineral and it ends up in the grain, provided the plant is grown in soil and water containing arsenic. And in many parts of the world, the water used to flood rice paddies is often high in arsenic.

Experts advise that to cut down on your arsenic exposure from rice you should eat more white rice than brown rice. Arsenic is often concentrated in the outer part of the rice kernel – the part of the rice that is removed to make white rice but is left intact on brown rice.

That’s unfortunate, because higher-fiber brown rice is otherwise the healthier choice, while low-fiber white rice is a high-glycemic food that spikes your blood sugar.

When you buy your rice, our sources suggest you should avoid rice grown in Texas, Missouri, Louisiana and Mississippi. In those states the crop is often raised in areas that had previously been cotton fields treated with arsenic-containing pesticides.

A better choice is white rice grown in California. Other experts recommend buying rice grown near the Himalayas like Northern Pakistan and Northern India.4 I expect it may be hard to find, and more expensive.

Other methods for limiting how much arsenic you consume include:

  • Vary your diet. Healthy foods like cruciferous vegetables have natural anti-cancer nutrients, but they also contain arsenic. Cauliflower, broccoli and Brussels sprouts are among the possible culprits. So don’t overdo these foods. Consume a wide variety of vegetables in your diet.
  • If you get your drinking water from a private well, have it tested for arsenic.
  • When cooking rice: Rinse it off before you cook it. This can eliminate some of the arsenic. Add plenty of water to your rice and drain the rice to eliminate more potential arsenic. Some experts advise using a ratio of six times as much water as rice and then draining off the extra water. I’ve never cooked rice using this method. The more common ratio is two-to-one or one-and-a-half to one, and you cook until the rice absorbs all the water.
  • Don’t overdo your consumption of wine and beer. These, too, can contain arsenic. The researchers at Dartmouth point out that the filtering systems used to make wine and beer may add arsenic to the beverages and they advise limiting how much you drink.5 One beverage distributor who is suing wine makers over the arsenic found in wine claims that, according to lab analyses he has paid for, the cheaper the wine the more likely it is to contain high levels of arsenic.
  • Stay away from rice milk which can be fairly high in arsenic. And limit foods that are sweetened with rice syrup.6
The long-term problem. . .

Unfortunately, after you’ve been exposed to arsenic, your increased risk for cancer can persist for decades.

According to a study in South America by researchers from UCLA and the Pontifical Catholic University of Chile, in some cases excessive arsenic in your food can increase your risk of cancer for at least 40 years.

Their research, performed in a town that had high levels of arsenic in drinking water that was cleaned up in 1970, found that people were stilldying at higher-than-average rates from lung, bladder, and kidney cancer in 2010.

The scientists believe this delay between exposure to arsenic and the development of arsenic-linked cancer represents one of the longest latency periods found for any human carcinogen.7

As you look for ways to mitigate the health problems linked to arsenic, getting enough folate in your diet may help.9 And there’s some evidence that drinking green tea may also negate some of the ill effects of arsenic.9
 

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